Dr. Daniel Clark, MD

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Mitotrol

Good nutrition is the foundation of your body’s health.
























Even if you follow a healthy diet, nutritional experts say the quality of meats, fruits and vegetables has gone down dramatically because of processing, chemicals and toxins.

 

Our cells are responsible for everything our bodies do. Having cells that function optimally is like having an internal fountain of youth! It is for this reason that everyday more and more healthcare professionals are recommending Mitotrol, the revolutionary dietary supplement containing the nutrients your cells need.

Nowadays, our lifestyles leave little time to plan meals, and we usually fill our diets with empty calories that come from low-quality fast foods.

Prepared and packaged foods make life easy, but they don’t provide all the nutrients your body needs.

 

Without gasoline, a car cannot run. Without energy, humans will begin feeling sick and weak. The human body needs the right fuel to properly feed the cells. This is where Mitotrol comes in.

An all-natural food, Mitotrol is immediately recognized and utilized by the body for its cellular energy, which aids the body to function at its best. Since Mitotrol is easily absorbed by the cells, the added saccharides and peptides enhance energy production, making the cells function effectively.

A fully-functioning cell promotes rapid repair and regeneration, helping organs function properly, making you feel healthy and full of energy.

The food you need



 

Mitotrol’s exclusive formula is a unique combination of ingredients that nourishes the mitochondria—the powerhouse of the cells—improving how the cells of your body and mind work.

First, we take a special blend of wholegrain rice cultivated in Thailand, one of the World’s most fertile and pristine regions, free of contaminants. Due to the purity of the land, this special rice contains a high concentration of nutrients, making it especially unique.

Next, this nutrient-packed wholegrain rice is combined with Spirulina, a potent blue-green algae loaded with antioxidants. This powerful team provides vital elements to the cells, allowing them to produce their own energy and synthesize new proteins.

More than just rice

Rice has a long history of cultivation, and its origins date back to various ancient cultures in China, India and Southeast Asia.


 








 

Benefits

Mitotrol is suitable for all ages, and has no known secondary side-effects. It has shown to help with:

Speeding up metabolism

Breaking down fats and reducing cholesterol

Brain and bone development for children

Reduces hair loss and repairs brittle hair

Stimulation of collagen production, improving skin’s elasticity

Promotes restful sleep

Stress reduction

Controls hyperactivity in children

General detoxification

Regulation of menstruation and reduction in menstrual pains

Reducing the effects of menopause

Reducing symptoms associated with rheumatoid arthritis

Improvement of personality disorders

Strengthening the immune system

Controlling epileptic seizures

Reduction in symptoms of depression

Regulation of bowel movements

Libido enhancement

Liver detoxification

Memory improvement and enhancement

Reducing the effects of Chronic Fatigue Syndrome

Regulation of blood sugar

Healing of bone, skin and muscle tissue

Creation of creatine (for muscle building)

Improving allergies

Media:

                  Doctor Version                                               Patient Version

In 2008 the FDA (Federal Food and Drug Administration) recognized that wholegrain rice is beneficial in fighting heart disease and some types of cancer, and that it is esteemed as one of the healthiest foods due to the great benefits it provides.

The nutritional spectrum of wholegrain rice provides the body with valuable minerals, such as magnesium, which plays an important role in muscular contraction and relaxation, helping to improve cardiovascular health.

Furthermore, it activates enzymes and helps the bones, joints, teeth, and cartilage stay strong. It also provides phosphorus, and calcium, which are both essential to the production of energy and the strengthening of the cells.

Rice also contains iron, which is necessary in hemoglobin production (the substance contained in the red blood cells, which transports oxygen to the blood) and myoglobin (which, transports oxygen to the muscles.)

Many of rice´s nutrients are found in the outer husk, and this non-refined part is easy for the body to absorb. The more refined or processed the rice is, the less vitamins and minerals it contains.

Mitotrol is produced using specially-selected non-refined rice grains, which undergo a proprietary bio-technical hydrolysis process. The precise science involved allows the polysaccharide peptides to have 90 percent or more absorption at the cellular level without damaging the Polypeptide protein fraction of the molecules, allowing the proteins to be more easily absorbed directly into the cells.

In order to stay strong and healthy, cells need ATP, which is fuel for the powerhouse of the cells, the mitochondria. Today’s processed, microwaved and pre-packaged meals include between 2 and 23 ATP molecules, which is not nearly enough to allow cells to self-protect, self-repair, renovate and self-heal.

Thanks to its proprietary scientific process, the molecules in Mitotrol are small enough to enter the cells, delivering more ATP molecules to the mitochondria! This means more energy and strength for each and every cell, allowing it to complete its natural cycle, and, better overall health and vitality to you.

The Science behind the ingredients


Mitotrol contains three elements that give it nutritional power: polysaccharides, peptides, and spirulina blue-green algae. In order to understand the power and efficacy of Mitotrol, it is essential to understand the properties of each of its components.









REFERENCES:

-Alberts, B., Bray, D., Lewis, J., Raff, M., Roberts, K., Watson, J. D. (1994) Molecular biology of the cell. Third edition. pp 43-45. New York. Garland Publishing, Inc.

-Rémésy, C., (2004) Alimentación y salud. 1ra edición. pp 11 y 12. Buenos Aires. Siglo XXI Editores Argentina, S.A.






 







 









REFERENCES:

-Alberts, B., Bray, D., Lewis, J., Raff, M., Roberts, K., Watson, J. D. (1994) Molecular biology of the cell. Third edition. Pp 22, 73-74. New York. Garland Publishing, Inc.

-Rémésy, C., (2004) Alimentación y salud. 1ra edición. pp 22-23. Buenos Aires. Siglo XXI Editores Argentina, S.A.






 
 

These are large chains of sugars (glucose) joined together, serving as a sort of storage room for the cells. The most common polysaccharides are starch (found in plants) and glycogen, stored in the livers of animals.

Each and every one of our cells are required to produce their own energy using different elements, such as sugars, fat, or proteins. Sugars are our principal source of energy used in the short-term. In fact, around 50% of the energy our bodies use comes from sugars.

If the ingested sugars are simple, such as the ones in sweeteners, it’s better for the body if they are ingested through cereals and legumes because their absorption is slower, and provides fiber, vitamins and minerals.

 

 


Peptides are small chains of amino acids. Amino acids are units that are composed of proteins, elements vital to the functioning of our bodies, which represent approximately half of the dry weight of a cell. They are the proteins in charge of carrying out functions as diverse as catalysis, intercellular recognition, and also the duplication and replication of genetic material.

 

The proteins that carry out functions inside our bodies are held together by our cells using the information contained within our DNA. They create different amino acid sequences, amino acids being the essential units that compose proteins. The sequence of these amino acids determines characteristics such as shape, function and interaction with other proteins.

There are 20 different kinds of amino acids that make up our proteins, and that are found within all living things, be they animals, proteins, bacteria, etc. All except for nine of these amino acids can be produced by our bodies. These are known as essential amino acids, which should be included in our diets. The proteins in our bodies are constantly being renewed, and many of the amino acids that make them up are recycled. Nevertheless, recycling is 100% effective, but requires that a certain amount of proteins be consumed so that our required amino acid levels are met. In some cases, such as during a growth spurt, more proteins may be required.

The proteins we consume in our diets are used for one of two things:

  1. 1.Providing the components necessary for the synthesis of new proteins, covering our amino acid requirements.

  2. 2.The generation of energy. Approximately 15% of the energy used by our body comes from proteins.

Creation of new proteins means more energy and cellular health, which in turn means a better quality of life.



Is a blue-green algae that’s part of the common, traditional diet in certain areas of Mexico and countries in Africa. It is among the oldes forms of life on the planet, in alkaline volcano lakes for around 3,500 million years.

Spirulina contains a significant amount of various proteins, which are easily absorbed by the body. These include:

  1. 1.Essential amino acids (those our body cannot produce on its own)

  2. 2.Vitamins

  3. 3.Minerals

  4. 4.Beta-carotene

  5. 5.Polysaccharides

  6. 6.Glucolipids and essential fatty acids

 






 

Scientific studies report that:

  1. 1.Spirulina extract has the ability to increase the activity of the immune system and has anti-viral and cancerogenic properties.

  2. 2.Consuming spirulina has been linked to decreases in the levels of cholesterol.

  3. 3.The human consumption of spirulina significantly reduces the concentrations of triacylglycerol and colesterol in the bloodstream, and also reduces bloodpressure.

  4. 4.Taking spirulina reduces the levels of glucose, cholesterol and triglycerides in the blood of patients with type 2 diabetes (Parikh et al, 2001.)

  5. 5.Spirulina can make the immune system stronger. A Japanese research team administered spirulina extract to a group of humans over the course of two months. They measured various parameters of immune system activity before and after the spirulina was administered. They found that, in 50% of the volunteers, the isolated NK blood cells (a type of cellular immune system that eliminates cells infected by viruses, and others with tumors) were showing more activity.

  6. 6.Including spirulina in a chicken´s daily diet increased the production capacity of antibodies, and of NK cell activity.

  7. 7.Some compounds found in spirulina have antiviral abilities. For example, the in vitro application of Spirulina maxima blocked the infection caused by viruses such as herpes simplex, pseudorabies, and human cytomegalovirus (HCMV.)

  8. 8.Aqueous Spirulina platensis extract, (also known as Arthrospira platensis), inhibits 50% of the replication of the HIV/AIDS virus-1 in lines of human lymphocytes.

  9. 9.Phycocyanin C, a component found in spirulina, induces death in a cellular line of leukemia. Also, calcio-spirulina, a component found in spirulina, inhibits the tumor invasion of cellular lines of melanoma, carcinoma of the colon as well as fibrosarcoma. It considerably reduces the metastasis of a cellular line in the lungs as well.

  10. 10.The consumption of spirulina maxima can protect mice against the neuro-toxic effects of MPTP (a drug used to induce a rodent version of Parkinson´s disease.) Researchers found that mice that had consumed spirulina over 14 days showed a considerable reduction in the MPTP effect. This may be due to the antioxidants contained in spirulina.

 


REFERENCES:

-Al-Batshan, H. A., Al-Mufarrej, S. I., Al-Homaidan, A. A., Qureshi, M. A. (2001) Enhancement of chicken macrophage phagocytic function and nitrite production by dietary Spirulina platensis. Immunopharmacol Immunotoxicol. 23(2):281-289.

-Alberts, B., Bray, D., Lewis, J., Raff, M., Roberts, K., Watson, J. D. (1994) Molecular biology of the cell. Third edition. pp 1164. New York. Garland Publishing, Inc.

-Ayehunie, S., Belay, A., Baba, T. W., Ruprecht, R. M. (1998) Inhibition of HIV-1 replication by an aqueous extract of Spirulina platensis (Arthrospira platensis). J Acquir Immune Defic Syndr Hum Retrovirol. 1;18(1):7-12.

-Chamorro, G., Pérez-Albiter, M., Serrano-García, N., Mares-Sámano, J. J., Rojas, P. (2007) Spirulina maxima pretreatment partially protects against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine neurotoxicity. Nutritional Neuroscience. 9(5/6): 207–212.

-Hernández-Corona, A., Nieves, I., Meckes, M., Chamorro, G., Barron, B. L. (2002) Antiviral activity of Spirulina maxima against herpes simplex virus type 2. Antiviral Res. 56(3):279-285.

-Hirahashi, T., Matsumoto, M., Hazeki, K., Saeki, Y., Ui, M., Seya, T. (2002) Activation of the human innate immune system by Spirulina: augmentation of interferon production and NK cytotoxicity by oral administration of hot water extract of Spirulina platensis. Int Immunopharmacol. 2(4):423-434.

-Khan, Z., Bhado, P., Bisen, P. S. (2005) Nutritional and Therapeutic Potential of Spirulina. Current Pharmaceutical Biotechnology. 6:373-379.

-Kim, H. M., Lee, E. H., Cho, H. H., Moon, Y. H. (1998) Inhibitory effect of mast cell-mediated immediate-type allergic reactions in rats by spirulina. Biochem Pharmacol. 55(7):1071-1076.

- Mishima, T., Murata, J., Toyoshima, M., Fujii, H., Nakajima, M., Hayashi T., Kato, T., Saiki, I. (1998) Inhibition of tumor invasion and metastasis by calcium spirulan (Ca-SP), a novel sulfated polysaccharide derived from a blue-green alga, Spirulina platensis. Clin Exp Metastasis. 16(6):541-550.


-Parikh, P., Many, U., Iyer, U. (2001) Role of Spirulina in the Control of Glycemia and Lipidemia in Type 2 Diabetes Mellitus. J Med Food. 4(4):193-199.

-Qureshi, M. A., Ali, R. A. (1996a) Spirulina platensis exposure enhances macrophage phagocytic function in cats. Immunopharmacol Immunotoxicol. 18(3):457-463.

-Qureshi, M. A., Garlich, J. D., Kidd, M. T. (1996b) Dietary Spirulina platensis enhances humoral and cell-mediated immune functions in chickens. Immunopharmacol Immunotoxicol. 18(3):465-76.

-Remirez, D., Ledón, N., González, R. (2002) Role of histamine in the inhibitory effects of phycocyanin in experimental models of allergic inflammatory response. Mediators Inflamm. 11(2):81-85.

-Subhashini, J., Mahipal, S. V., Reddy, M. C., Mallikarjuna Reddy M., Rachamallu, A., Reddana P. (2004) Molecular mechanisms in C-Phycocyanin induced apoptosis in human chronic myeloid leukemia cell line-K562. Biochem Pharmacol. 68(3):453-462.

-Thaakur, S. R., Jyothi, B. (2007) Effect of spirulina maxima on the haloperidol induced tardive dyskinesia and oxidative stress in rats. J Neural Transm. 114(9):1217-25.

-Torres-Duran, P. V. (2007) Antihyperlipemic and antihypertensive effects of Spirulina maxima in an open sample of mexican population: a preliminary report. Lipids Health Dis. 6(1):33.

The leader in alpha glucan technology


 

 

 

 

Mitotrol contains a high concentration of mostly alpha glucans and some beta glucans (alpha polysaccharides peptides) derived from brown rice through a proprietary process that employs:

  1. 1.Cross pollination of 3 special strains of rice to increase nutrients

  2. 2.Nanotechnology is used to reduce the ingredients to one millionth of a unit

  3. 3.It takes 100 pounds of rice to make one pound of Mitotrol

Alpha glucans are more bio-available than beta glucans and easily assimilated by the mitochondria to create ATP or cellular energy. According to Robert K. Naviaux, MD, PhD of A Primary Care Physician’s Guide, Mitochondrial biology is one of the fastest growing areas in genetics and medicine, connecting scientific disciplines ranging from embryology to cancer, to infectious disease. Indeed, disturbances in mitochondrial metabolism are now known to play a role not only in rare childhood diseases, but have also been implicated in many common diseases of aging, including heart disease, diabetes, Parkinson disease, and dementia.

Although most studies on plant glucans have been done on beta glucans from mushrooms, which also contain a small amount of alpha glucans, alpha glucans are smaller and easier to utilize by the cells of the body. Mitotrol is the first product to come to the market with a flip-ratio of alpha to beta glucans is proving to be just as effective as beta glucans from mushrooms and in most cases more powerful.

 

Other useful studies on Alpha-glucans

Anti-diabetic effects of Alpha-glucans
J Pharm Pharmacol. 2007 Apr;59(4):575-82. Anti-diabetic effect of an alpha-glucan from fruit body of maitake (Grifola frondosa) on KK-Ay mice. Hong L, Xun M, Wutong W. School of Life Science and Technology, China Pharmaceutical University, Nanjing 210009, China. PMID: 17430642 [PubMed - indexed for MEDLINE]

Reducing the inflammation in Colitis with Alpha-glucans
Br J Nutr. 2009 Sep 22:1-10. [Epub ahead of print] Lavi I, Levinson D, Peri I, Nimri L, Hadar Y, Schwartz B.
Institute of Biochemistry, Food Science and Nutrition, Faculty of Agricultural, Food and Environmental Quality Sciences, The Hebrew University of Jerusalem, Rehovot 76100, Israel.PMID: 19772681 [PubMed - as supplied by publisher]

Alpha and beta glucans increase cellular ATP levels
(Reported XU C.F et al in ZHU J-S, Halpern GM, Jones K. The Scientific rediscovery of a precious ancient Chinese herbal regimen: Cordyceps sinensis: Part I. J Alt Comp Med 1998;4(3):289-303.)








Unlocking a Major Cause of Disease

Mitochondrial medicine, new on the medical scene, is a rapidly developing science.


 

 

 


Even though mitochondrial disease research dates back to the 1940s, the first diagnosis of a mitochondrial disorder dates back to 1959. In 1963, researchers uncovered a different type of DNA in mitochondria creating its own blueprint (mtDNA) that differed from nuclear DNA (nDNA) found in the nucleus of cells.

Today, mitochondrial research involves a multitude of medical specialists, including:

  1. 1.Doctors specializing in metabolic diseases

  2. 2.Cell biologists

  3. 3.Molecular geneticists

  4. 4.Neurologists

  5. 5.Biochemists

  6. 6.Pathologists

  7. 7.Immunologists

  8. 8.Chiropractors

  9. 9.Embryologists

Mitochondrial and metabolic medical conditions, including more than 40 different identified diseases with varying genetic features, are called mitochondrial cytopathies. Each shares the common factor of having the inability to completely burn food and oxygen to generate energy.

Within each cell, mitochondria are tiny energy “factories” converting chemical fuel into energy. More and more research indicates that mitochondria play a vital role in aging and age-related ailments, such as type 2 diabetes, Parkinson’s, Alzheimer's and heart disease. In older adults, mitochondria function less efficiently than in younger people. This is a change that may be related to insulin resistance, a trigger for diabetes.


Are mitochondria responsible for a cell’s survival?



Research found that genetically-engineered cells with higher levels of a mitochondrial enzyme (NAMPT) were better protected and more resistant to dying when subjected to toxic chemicals. Research also found that as long as the cells' mitochondria were healthy, they could maintain themselves regardless of their condition.


What are the symptoms of mitochondrial diseases?

Mitochondrial diseases are categorized according to the symptoms they present to various organs, including:

  1. 1.Brain

  2. 2.Nerves (including nerves to stomach and intestines)

  3. 3.Muscles

  4. 4.Kidneys

  5. 5.Heart

  6. 6.Liver

  7. 7.Eyes

  8. 8.Ears

  9. 9.Pancreas

In some patients, a single organ may be affected; in others, all organs may be involved. Mitochondrial illnesses can also range in severity from mild to fatal.

Depending on which cells of the body are affected, symptoms might include:

  1. 1.Dementia (mental disorder characterized by confusion, disorientation, and memory loss)

  2. 2.Developmental delays, learning disabilities

  3. 3.Diabetes

  4. 4.Gastrointestinal disorders, Including severe constipation

  5. 5.Growth impeded

  6. 6.Heart, liver, or kidney disease

  7. 7.Increased risk of infection

  8. 8.Mental retardation

  9. 9.Muscle coordination loss and muscle weakness

  10. 10.Neurological problems, seizures

  11. 11.Respiratory disorders

  12. 12.Thyroid dysfunction

  13. 13.Visual impairment and/or hearing losses

Mitotrol nutritionally supports the mitochondria’s ability to create cellular energy


 


Mitotrol contains compounds (alpha glucans) classified as a non-dialyzable high molecular weight with low molecular weight polypeptides.

The molecular weights of the different compounds range from 150 to 300 kDa. A major chemical feature of Mitotrol is the presence of D-glucose units in the main chain. Side-chain D-glucose units are linked via a 1, 6 to the main chain with low molecular weight polypeptides representing 9.5 percent of the substance at non-reducing terminal.

These plant-based glucans give many plants their important medicinal properties. Alpha-glucans are much smaller in molecular size than the well-known beta glucans, and therefore, easily absorbed by the body.

The alpha glucans in Mitotrol come from combining specific families of whole grain rice taken through a proprietary process that provides a higher ratio of alpha to beta glucans. Whole grain rice in general contains much higher levels of alpha forms of glucans than beta. Since rice is safe for all blood types, Mitotrol is fast becoming the product of choice over many mushroom-based products where the ratio of alpha to beta glucans is reversed.

 

A recent independent study conducted by The Royal Thai Army Hospital and College of Medicine in conjunction with PMK Research Center, Bangkok, Thailand, and Emory University School of Medicine, Atlanta concluded: “The same whole grain rice polysaccharides and polypeptides in Mitotrol were shown to increase cellular energy (ATP) up to 54 percent. “

Results of these in vitro studies demonstrated that when neurotoxins were induced, they killed all the cells and severely damages the dendrites (fibers extending from the body of the cell). However, when neurons were pre-treated with rice polysaccharide peptides, they showed different levels of cell survival and apparent recovery of dendrites from the neurotoxin injuries within 48 hours. This study suggested that there may be a place for rice polysaccharide peptides in the nutritional support of brain-related injuries and diseases.

 

Other useful studies on Alpha-glucans

Anti-diabetic effects of Alpha-glucans
J Pharm Pharmacol. 2007 Apr;59(4):575-82. Anti-diabetic effect of an alpha-glucan from fruit body of maitake (Grifola frondosa) on KK-Ay mice. Hong L, Xun M, Wutong W. School of Life Science and Technology, China Pharmaceutical University, Nanjing 210009, China. PMID: 17430642 [PubMed - indexed for MEDLINE]

Reducing the inflammation in Colitis with Alpha-glucans
Br J Nutr. 2009 Sep 22:1-10. [Epub ahead of print] Lavi I, Levinson D, Peri I, Nimri L, Hadar Y, Schwartz B.
Institute of Biochemistry, Food Science and Nutrition, Faculty of Agricultural, Food and Environmental Quality Sciences, The Hebrew University of Jerusalem, Rehovot 76100, Israel.PMID: 19772681 [PubMed - as supplied by publisher]

Alpha and beta glucans increase cellular ATP levels
Cellular energy, which is also known scientifically as the ATP/IP ratio. Cordyceps has been clinically proven to increase cellular Bio-Energy by as much as 55% (Reported XU C.F et al in ZHU J-S, Halpern GM, Jones K. The Scientific rediscovery of a precious ancient Chinese herbal regimen: Cordyceps sinensis: Part I. J Alt Comp Med 1998;4(3):289-303.)

The statements contained within this website have not been evaluated by the FDA. This product is not intended to diagnose or cure any disease and is not intended to replace any medication.

If you have medical questions, please consult your personal healthcare provider.


Copyright © 2010 Mitotrol. All rights reserved.